产品货号：
Z37279
中文名称：
ERp57/ERp60/PDIA3抗体
英文名称：
Anti-ERp57/ERp60/PDIA3 Antibody (Clone#7E5)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ERp57/ERp60/PDIA3 Antibody (Clone#7E5) |
| 指标别名 | 58kDa microsomal protein;Disulfide isomerase ER 60;endoplasmic reticulum marker;ER protein 57;ER protein 60;ER60;ERp57;ERp57/ERp60;ERp60;ERp61;GRP57;GRP58;HsT17083;P58;PDIA3;PI PLC;Protein disulfide isomerase A3 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | PDIA3 |
| 克隆号 | 7E5 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ERp57 (471-505aa RELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL),different from the related mouse and rat sequences by two amino acids. |
| 实际分子量 | 57KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PDIA3 (Protein disulfide isomerase family A,member 3),also called GRP58,Erp57 or ER60,is an isomerase enzyme.It is mapped on 15q15.3.PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex,which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins.The protein was once thought to be a phospholipase;however,it has been demonstrated that the protein actually has protein disulfide isomerase activity.It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. |
| Uniprot ID | P30101 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P). |
| 基因名全称 | protein disulfide isomerase family A,member 3 |
| 蛋白名全称 | Protein disulfide-isomerase A3 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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